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How to take this medication
 Swallow this medication whole. Do not crush or chew them or the sustained
activity of the drug will be destroyed and the chances of side effects
occurring may be increased. Take as directed, usually twice daily for 7 to
12 weeks. Do not take more or less medication than prescribed. Since this
drug can cause sleeplessness at first, it is best not to take near
bedtime. It is advised to continue smoking for the first week after
starting this drug, until it reaches higher levels in your blood. Do not
smoke if using any nicotine products with this drug. Too much nicotine can
cause serious side effects.
Side Effects
Zyban is generally well tolerated. Dry mouth, headache, increased
sweating, constipation, anxiety and fatigue may occur. If these effects
persist or worsen, notify your doctor.
Precautions
Before taking bupropion tell your doctor if you have a history of
seizures, head injury, brain tumor; heart, liver or kidney disease, an
eating disorder or any mental conditions, diabetes or if you have any
allergies. Limit or avoid consumption of alcoholic beverages; alcohol can
increase your risk of seizures. Chronic alcohol users who suddenly stop
the intake of alcohol while taking bupropion may increase the risk of
having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam,
chlordiazepoxide) is not recommended because doing so may increase the
risk of having seizures. Elderly patients may be more sensitive to the
effects of this drug. Tell your doctor if you are pregnant or plan to
become pregnant before taking this drug. This drug is excreted into breast
milk. Because of the potential risk to the infant, breast-feeding while
using Zyban is not recommended. Consult your doctor before breast-feeding.
Drug Interactions
Before taking bupropion tell your doctor of all nonprescription and
prescription medications you may use especially MAO inhibitors (e.g.,
isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline,
furazolidone), levodopa, theophylline, corticosteroids (e.g., prednisone),
seizure medications, sedatives, ritonavir, tranquilizers/psychiatric drugs
(e.g., chlorpromazine), other antidepressants (e.g., amitriptyline),
salicylates (e.g., aspirin, salsalate), isoniazid, chlolinesterase
inhibitors (e.g., tacrine, donepezil), morphine, and adrenaline-like drugs
(e.g., pseudoephedrine). Excess caffeine intake can increase the chance of
seizures with this drug. Check all nonprescription/prescription drug
labels for caffeine. Consult doctor or pharmacist. A certain product used
to help quit smoking contains bupropion. Do not take that product while
using this one.
Missed Dose
Take any missed dose as soon as possible but not if it is within 8 hours
of the next dose. If it is time for the next dose, skip the missed dose
and resume your regular schedule. Do not "double up" the dose.
Storage
Store at room temperature away from sunlight and moisture. Keep this and
all medications out of the reach of children.
[ Zyban Information ] [ Zyban Side Effects ]
Be a Quitter: Help for Smokers
Most smokers know that quitting is not easy. That's because nicotine can be
powerfully addictive, both physically and mentally. Quitting "cold turkey"
can cause withdrawal symptoms such as fatigue, trouble concentrating,
irritability, and cigarette cravings. Fortunately, help is available through
various forms of nicotine replacement therapy. There's also a prescription
drug called buproprion (trade name ZybanŽ) that lessens symptoms.
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